Small-angle scattering for characterization of pharmaceutical materials
نویسندگان
چکیده
Small-angle scattering (SAS) is a versatile analytical technique that provides detailed structural information from sample at the length scale of nanometers. In this overview, we discuss basic principles SAS and diverse applications in characterization pharmaceutical materials. Examples include identification liquid-crystalline mesophase drugs, influence excipient microstructure on final product performance, formulation optimization solid dispersions as well protein-based therapeutics.
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ژورنال
عنوان ژورنال: Trends in Analytical Chemistry
سال: 2021
ISSN: ['1879-3142', '0165-9936']
DOI: https://doi.org/10.1016/j.trac.2020.116144